Triple Bioorthogonal Ligation Strategy for Simultaneous Labeling of Multiple Enzymatic Activities

TitleTriple Bioorthogonal Ligation Strategy for Simultaneous Labeling of Multiple Enzymatic Activities
Publication TypeJournal Article
Year of Publication2012
AuthorsWillems, L.I., N. Li, B.I. Florea, M. Ruben, G.A. van der Marel, H.S. Overkleeft
JournalAngewandte Chemie-International Edition
Volume51
Issue18
Pagination4431-4434
ISBN Number1433-7851
Accession NumberISI:000303158300037
Keywordsactivity-based profiling, amino-acids, bioorthogonal reactions, click chemistry, copper(i)-catalyzed azide-alkyne, cycloadditions, in-vivo, inhibitor, living cells, proteasome probes, proteins, terminal alkynes, tetrazines
DOI10.1002/anie.201200923
Alternate JournalAngew Chem Int EditAngew Chem Int Edit

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