Activation of a Photodissociative Ruthenium Complex by Triplet-Triplet Annihilation Upconversion in Liposomes

TitleActivation of a Photodissociative Ruthenium Complex by Triplet-Triplet Annihilation Upconversion in Liposomes
Publication TypeJournal Article
Year of Publication2014
AuthorsAskes, S.H.C., A. Bahreman, S. Bonnet
JournalAngewandte Chemie-International Edition
Volume53
Issue4
Pagination1029-1033
Date PublishedJan 20
ISBN Number1433-7851
Accession NumberWOS:000329879500020
Keywordsagents, chemotherapy, light, liposomes, membranes, phase, photochemistry, polymer-films, polypyridyl complexes, prodrug, proteins, ruthenium, strategy
Abstract

Liposomes capable of generating photons of blue light insitu by triplet-triplet annihilation upconversion of either green or red light, were prepared. The red-to-blue upconverting liposomes were capable of triggering the photodissociation of ruthenium polypyridyl complexes from PEGylated liposomes using a clinical grade photodynamic therapy laser source (630nm).

DOI10.1002/Anie.201309389
Alternate JournalAngew Chem Int Edit

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