Dr. Wachten studies cilia, which are organelles that cause movement on the surface of mammalian cells, such as those clearing mucus from the lungs and the flagellum of the sperm cell. Their dysfunction can lead to many diseases ranging from lung and kidney disease to, of course, infertility.
Despite its pivotal role in many processes, this organelle is poorly understood. It is Dr. Wachten’s research aim to understand the function of these organelles in space and time using a combination of optogenetic approaches, genetically encoded biosensors and high res microscopy techniques. In short, a truly interdisciplinary approach to tackle an important biological phenomenon.
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