Our focus

Twenty years from now, the world population is estimated to be around 8.3 billion people (now 7.3 billion). In combination with the improvements in living standards and the corresponding growth in consumption, this will result in an enormous increase in the demand for food, consumables, water and energy. Technological and fundamental chemical solutions to meet these demands are needed.

Chemical biology research at the Leiden Institute of Chemistry is aimed at understanding biological processes at the molecular level to strengthen the knowledge base of human health and disease. The approach to achieve this goal is a fundamental chemical one; with the aid of chemical probes biological systems are interrogated.


In memoriam: Dr. Harry Jacobs

Met spijt delen wij mee dat op 22 mei 2016 op 85-jarige leeftijd onze oud-collega dr. Harry Jacobs is overleden.

Breakthrough by Leiden researchers in Pompe disease

Researchers at Leiden University have made a breakthrough in the study of the hereditary Pompe disease. Together with colleagues in York, they have developed a molecule that binds to the enzyme that is key to the progress of the disease. The findings have been published in ACS Central Science.

Groente, fruit en bloemen langer houdbaar met nieuwe sensor

Als groente en fruit rijp worden, komt het gas etheen vrij. Etheen beïnvloedt ook de snelheid van de rijping. Chemicus Tom van Dijkman onderzocht hoe kleine en goedkope sensoren gemaakt kunnen worden om etheenconcentraties te meten tijdens het transport. Promotie op 12 mei 2016.

Double-stranded water on platinum on the cover of PRL


A paper by Manuel Kolb on water adsorption on stepped platinum surfaces, in collaboration with the group of Dan Killelea at Layola University in Chicago, features on the cover of Physical Review Letters.

Boost of Water Electrolysis - Article In Nature Communications

Researchers from Leiden University, Ruhr-Universität Bochum and the Technical University of Munich have boosted the efficiency of water electrolysis. They located a layer of copper atoms near the surface of conventional platinum electrodes.

NWO awards 1.5 million euro VICI grant to Remus Dame

NWO has awarded a prestigious VICI grant to Remus Dame. With this grant he will strengthen his research programme on dynamic organization of the bacterial genome. Specifically, he will investigate the molecular mechanisms that drive changes in genome organization in response to environmental cues, the effect of these changes on specific environmentally regulated genes and the resulting physiological response.

Water at stepped platinum surface on the cover of PCCP

A paper by Manuel Kolb on the adsorption of water on the stepped Pt(533) surface features on the cover of PCCP:


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